Kadcyla - Top-Selling Antibody Drug Conjugate (ADC) | Biopharma PEG
How KADCYLA® (ado-trastuzumab emtansine) is Designed to Work in EBC
Trastuzumab emtansine - Wikipedia
Trastuzumab emtansine - Wikipedia
Structural components of Kadcyla (Adaptation from Kitson et al. [8]). | Download Scientific Diagram
Structure of an antibody drug conjugate (ADC) Kadcyla s. SMCC linker... | Download Scientific Diagram
Ado-trastuzumab emtansine) | CancerQuest
Structural Characterization of Cross-Linked Species in Trastuzumab Emtansine (Kadcyla) | Bioconjugate Chemistry
Kadcyla: The Next Standard in Breast Cancer Therapy? – OncoBites
FDA approves Kadcyla (ado-trastuzumab emtansine), a new therapy for patients with HER2-positive, late-stage (metastatic) breast cancer. | New Drug Approvals
Kadcyla - Top-Selling Antibody Drug Conjugate (ADC) | Biopharma PEG
Kadcyla - Top-Selling Antibody Drug Conjugate (ADC) | Biopharma PEG
Molecules | Free Full-Text | An Insight into FDA Approved Antibody-Drug Conjugates for Cancer Therapy
Kadcyla: Package Insert - Drugs.com
Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance | Nature Communications
Mechanisms of resistance to trastuzumab emtansine (T-DM1) in HER2-positive breast cancer | British Journal of Cancer
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Trastuzumab-Emtansin – Wikipedia
EPosters - Kadcyla - Top-Selling Antibody Drug Conjugate (ADC)
Informatics Considerations at the Dawn of the Antibody Drug Conjugate Era - Collaborative Drug Discovery Inc. (CDD)
Preparation and characterization of antibody-drug conjugates acting on HER2-positive cancer cells | PLOS ONE
Recent developments in chemical conjugation strategies targeting native amino acids in proteins and their applications in antibody–drug conjugates - Chemical Science (RSC Publishing) DOI:10.1039/D1SC02973H
Biomedicines | Free Full-Text | Advances and Limitations of Antibody Drug Conjugates for Cancer
Structure–Activity Relationships of Antibody-Drug Conjugates: A Systematic Review of Chemistry on the Trastuzumab Scaffold | Bioconjugate Chemistry
Roche | Kadcyla (trastuzumab emtansine)
SID 135353969 - PubChem
Perspectives and Characterization on Antibody–Drug Conjugates
Kadcycla ADC - Potency Regulatory and Bioprocessing Concerns of ADCs - BioProcess InternationalBioProcess International
Physical characteristics comparison between maytansinoid-based and auristatin-based antibody-drug conjugates
Kadcyla and HER2-Positive Breast Cancer: Understanding the Science Behind the Drug
Kadcyla (Trastuzumab Emtansine) for Treatment of Breast Cancer - Clinical Trials Arena
Site-selective modification strategies in antibody–drug conjugates - Chemical Society Reviews (RSC Publishing) DOI:10.1039/D0CS00310G
Antibody–Drug Conjugates: Perspectives and Characterization
Antibody–Drug Conjugates | Encyclopedia MDPI
Biological Evaluation of Maytansinoid-Based Site-Specific Antibody-Drug Conjugate Produced by Fully Chemical Conjugation Approach: AJICAP®
Pharmaceutics | Free Full-Text | Linkers: An Assurance for Controlled Delivery of Antibody-Drug Conjugate
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Kadcyla: The Next Standard in Breast Cancer Therapy? – OncoBites
Structure–Activity Relationships of Antibody-Drug Conjugates: A Systematic Review of Chemistry on the Trastuzumab Scaffold | Bioconjugate Chemistry
RCSB PDB - IL1 Ligand Summary Page
Recent developments in chemical conjugation strategies targeting native amino acids in proteins and their applications in antibody–drug conjugates - Chemical Science (RSC Publishing) DOI:10.1039/D1SC02973H
Introducing Glycolinkers for the Functionalization of Cytotoxic Drugs and Applications in Antibody–Drug Conjugation Chemistry - Ekholm - 2016 - ChemMedChem - Wiley Online Library
Structure–Activity Relationships of Antibody-Drug Conjugates: A Systematic Review of Chemistry on the Trastuzumab Scaffold | Bioconjugate Chemistry
Full article: In-depth structural characterization of Kadcyla® (ado-trastuzumab emtansine) and its biosimilar candidate
Vedotin - an overview | ScienceDirect Topics
Emerging classes of armed antibody therapeutics against cancer - MedChemComm (RSC Publishing) DOI:10.1039/C3MD00360D
Mechanisms of resistance to trastuzumab emtansine (T-DM1) in HER2-positive breast cancer | British Journal of Cancer
Selective Chemical Modification to the Higher‐Order Structures of Nucleic Acids - Nagatsugi - 2023 - The Chemical Record - Wiley Online Library
Antibody–drug conjugates for cancer - The Lancet
ADCs on the Market and in Clinical Development | SpringerLink
In-depth structural characterization of Kadcyla® (ado-trastuzumab emtansine) and its biosimilar candidate. - Abstract - Europe PMC
Fam-trastuzumab deruxtecan-nxki | New Drug Approvals
Frontiers | Crystallizable Fragment Glycoengineering for Therapeutic Antibodies Development
An Insight into FDA Approved Antibody-Drug Conjugates for Cancer Therapy
NJ Bio, Inc. — ADC Payload Classes
LC–MS bioanalysis of Trastuzumab and released emtansine using nano-surface and molecular-orientation limited (nSMOL) proteolysis and liquid–liquid partition in plasma of Trastuzumab emtansine-treated breast cancer patients - ScienceDirect
More than Toxins—Current Prospects in Designing the Next Generation of Antibody Drug Conjugates
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Biopharma PEG Scientific Inc. (@biochempeg) / Twitter
Biophysical Properties and Heating-Induced Aggregation of Lysine-Conjugated Antibody-Drug Conjugates - Journal of Pharmaceutical Sciences
ADCs
How KADCYLA® (ado-trastuzumab emtansine) is Designed to Work in EBC
CS 2019.02.01.14 - Bionatura
5-Hydroxytryptophan, methyl, 3-PFP - Chemical & Physical Properties by Cheméo
Perspectives and Characterization on Antibody–Drug Conjugates
KADCYLA® (ado-trastuzumab emtansine) Metastatic Breast Cancer Brochure
Structure of Kadcyla ® | Download Scientific Diagram
Chemical Assembly of Antibody-Drug Conjugates | SpringerLink
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A Patent Review on FDA‐Approved Antibody‐Drug Conjugates, Their Linkers and Drug Payloads - Chia - 2022 - ChemMedChem - Wiley Online Library
Expanding the Horizon of Antibody-Drug Conjugates for Cancer Treatment
Frontiers | The Analysis of Key Factors Related to ADCs Structural Design
Kadcyla® (trastuzumab emtansine)
An Insight into FDA Approved Antibody-Drug Conjugates for Cancer Therapy
PK assays for antibody–drug conjugates: case study with ado-trastuzumab emtansine | Bioanalysis
Antibody–drug conjugates: Recent advances in linker chemistry - ScienceDirect
Determination of pharmacokinetics and tissue distribution of a novel lutetium-labeled PSMA-targeted ligand, 177Lu-DOTA-PSMA-GUL, in rats by using LC–MS/MS | Scientific Reports
The Pharmaceutical Industry in 2022: An Analysis of FDA Drug Approvals from the Perspective of Molecules. - Abstract - Europe PMC
EPosters - Directions for Next Generation Antibody-Drug Conjugates
What Are ADC Linkers: Cleavable vs. Non-Cleavable Linkers | Biopharma PEG
ADC linkers: Definition and examples - ProteoGenix
Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-β-boswellic acid in combination on isoproterenol-induced myocardial injury in rats Corrigendum in /10.3892/ijmm.2021.5067