The PHD finger of p300 Influences Its Ability to Acetylate Histone and Non- Histone Targets - ScienceDirect
PDF] Role of Histone acetyltransferase, “p300” in Human Cancer | Semantic Scholar
The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases: Cell
Regulation of CBP/p300 acetyltransferase activity by AIL, RING domain... | Download Scientific Diagram
A Read/Write Mechanism Connects p300 Bromodomain Function to H2A.Z Acetylation - ScienceDirect
SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53: Cell
Molecular model and controls showing that p300 acetyltransferase... | Download Scientific Diagram
The Identification of a Novel Natural Activator of p300 Histone Acetyltranferase Provides New Insights into the Modulation Mechanism of this Enzyme - Dal Piaz - 2010 - ChemBioChem - Wiley Online Library
P300 Chemiluminescent Assay Kit
Nucleosome eviction and activated transcription require p300 acetylation of histone H3 lysine 14 | PNAS
Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence - ScienceDirect
Small Molecule Modulators of Histone Acetyltransferase p300* - Journal of Biological Chemistry
E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair | Nature Communications
Transcriptional Regulation by Histone Acetylation and Deacetylation
Histone acetylation and deacetylation: importance in inflammatory lung diseases | European Respiratory Society
Cancers | Free Full-Text | CBP/p300: Critical Co-Activators for Nuclear Steroid Hormone Receptors and Emerging Therapeutic Targets in Prostate and Breast Cancers | HTML
Two Histone/Protein Acetyltransferases, CBP and p300, Are Indispensable for Foxp3+ T-Regulatory Cell Development and Function | Molecular and Cellular Biology
Differential contribution of p300 and CBP to regulatory element acetylation in mESCs | BMC Molecular and Cell Biology | Full Text
Autophagy regulation by acetylation—implications for neurodegenerative diseases | Experimental & Molecular Medicine
Model for functional effects of activator-dependent p300 histone... | Download Scientific Diagram
Discovery, Structure–Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP | Journal of Medicinal Chemistry
Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease
How are regions of DNA carrying acetylated histones recognized by enzymes? | Institute for Advanced Biosciences | Grenoble
Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription. - Abstract - Europe PMC
Promoter-specific changes in initiation, elongation, and homeostasis of histone H3 acetylation during CBP/p300 inhibition | eLife
The Wild-type and Gain-of-function Mutant p53 Enhance p300 Autoacetylation through Conformational Switching | bioRxiv
The pioneer factor activity of c-Myb involves recruitment of p300 and induction of histone acetylation followed by acetylation-induced chromatin dissociation | Epigenetics & Chromatin | Full Text
Frontiers | The Role of Histone Acetyltransferases in Normal and Malignant Hematopoiesis
Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents
Is histone acetylation the most important physiological function for CBP and p300? - Figure F2 | Aging
Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP | PNAS
Interplay between p300 and HDAC1 regulate acetylation and stability of Api5 to regulate cell proliferation | bioRxiv
Frontiers | The Role of Histone Protein Acetylation in Regulating Endothelial Function
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition,Molecular Cell - X-MOL
P300‐dependent acetylation of histone H3 is required for epidermal growth factor receptor‐mediated high‐mobility group protein A2 transcription in hepatocellular carcinoma - Liang - 2021 - Cancer Science - Wiley Online Library
P300-Mediated acetylation facilitates the transfer of histone H2A–H2B dimers from nucleosomes to a histone chaperone
Promoter-specific changes in initiation, elongation, and homeostasis of histone H3 acetylation during CBP/p300 inhibition | eLife
Roles of CREB-binding protein (CBP)/p300 in respiratory epithelium tumorigenesis | Cell Research
Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation - ScienceDirect
Changing the Selectivity of p300 by Acetyl-CoA Modulation of Histone Acetylation | ACS Chemical Biology
Involvement of p300/CBP and epigenetic histone acetylation in TGF-β1-mediated gene transcription in mesangial cells | American Journal of Physiology-Renal Physiology
Simultaneous single-molecule detection of the acetyltransferase and crotonyltransferase activities of histone acetylation writer p300 - Chemical Communications (RSC Publishing)
IJMS | Free Full-Text | Histone Acetylation Domains Are Differentially Induced during Development of Heart Failure in Dahl Salt-Sensitive Rats | HTML
Assays for Validating Histone Acetyltransferase Inhibitors | Protocol
ATRA transcriptionally induces nSMase2 through CBP/p300-mediated histone acetylation[S] - Journal of Lipid Research
Acetyltransferases (HATs) as Targets for Neurological Therapeutics | SpringerLink
PDF] Nucleosome eviction and activated transcription require p300 acetylation of histone H3 lysine 14 | Semantic Scholar
Histone Acetyltransferase Activity of p300 Is Required for the Promotion of Left Ventricular Remodeling After Myocardial Infarction in Adult Mice In Vivo | Circulation
H3.3 phosphorylation stimulates p300 histone acetyltransferase activity... | Download Scientific Diagram
A role for cofactor–cofactor and cofactor–histone interactions in targeting p300, SWI/SNF and Mediator for transcription | The EMBO Journal
Eurofins Discovery
Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents
Histone acetyltransferase p300/CBP inhibitor C646 blocks the survival and invasion pathways of gastric cancer cell lines
KAT3B-p300 Archives - Network of Cancer Research
Full article: Loci-specific histone acetylation profiles associated with transcriptional coactivator p300 during early myoblast differentiation
Active Motif offers a workflow of research tools and approaches to characterize the complex functions of p300/CBP
Histone Acetyltransferase p300/CREB-binding Protein-associated Factor (PCAF) Is Required for All-trans-retinoic Acid-induced Granulocytic Differentiation in Leukemia Cells* - Journal of Biological Chemistry
Down-Regulation of p300/CBP Histone Acetyltransferase Activates a Senescence Checkpoint in Human Melanocytes1
Dimethyl sulfoxide (DMSO) enhances direct cardiac reprogramming by inhibiting the bromodomain of coactivators CBP/p300 - Journal of Molecular and Cellular Cardiology
RCSB PDB - 3BIY: Crystal structure of p300 histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA
Publications — Ott Lab
Assays for Validating Histone Acetyltransferase Inhibitors | Protocol
Histone acetyltransferase - Wikipedia
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death | Science Advances
P300/CBP as a Key Nutritional Sensor for Hepatic Energy Homeostasis and Liver Fibrosis
The Dual Role Of Histone Acetylation In Stem Cells - Asian Scientist Magazine
KoreaMed Synapse
Coordinated Histone H3 Methylation and Acetylation Regulate Physiologic and Pathologic Fas Ligand Gene Expression in Human CD4+ T Cells | The Journal of Immunology
A Novel Activator of CBP/p300 Acetyltransferases Promotes Neurogenesis and Extends Memory Duration in Adult Mice | Journal of Neuroscience
Review The versatile functions of the transcriptional coactivators p300 and CBP and their roles in disease
Histone Acetyltransferase Inhibitor II | p300 Histone Acetyltransferase Inhibitor | MedChemExpress
Involvement of p300/CBP and epigenetic histone acetylation in TGF-β1-mediated gene transcription in mesangial cells | American Journal of Physiology-Renal Physiology
CRISPR-based Gene Activation
The TAZ2 domain of CBP/p300 directs acetylation towards H3K27 within chromatin | bioRxiv
Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch. - Abstract - Europe PMC
Acetylation of Histones and Transcription-Related Factors | Microbiology and Molecular Biology Reviews
APExBIO - Chromatin/Epigenetics - Signaling Pathways
P300/CBP Transcriptional Coactivator
The Key Role of DNA Methylation and Histone Acetylation in Epigenetics of Atherosclerosis
P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts - Gastroenterology
C646, a selective small molecule inhibitor of histone acetyltransferase p300, radiosensitizes lung cancer cells by enhancing mitotic catastrophe - Radiotherapy and Oncology
E2A and CBP/p300 Act in Synergy To Promote Chromatin Accessibility of the Immunoglobulin κ Locus | The Journal of Immunology
Discovery, Structure–Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP | Journal of Medicinal Chemistry
EP300 (E1A binding protein p300)
Histone Acetyltransferase Inhibitor II, p300/CBP HAT inhibitor (CAS 932749-62-7) (ab144556)
CBP/p300 Coactivators | SpringerLink
A Histone Acetyltransferase p300 ... preview & related info | Mendeley
Life and death of transcriptional co-activator p300
RSC_MB_C1MB05363A 1..9
Histone Acetylation Is Associated with Transcription Activation
Sirna Targeting P300 (Horizon Discovery) | Bioz | Ratings For Life-Science Research
TGF-β Induces Acetylation of Chromatin and of Ets-1 to Alleviate Repression of miR-192 in Diabetic Nephropathy | Science Signaling
P300-Mediated acetylation facilitates the transfer of histone H2A–H2B dimers from nucleosomes to a histone chaperone
Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity | Circulation
CIPSM - The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases
Live‐Cell Studies of p300/CBP Histone Acetyltransferase Activity and Inhibition - Dancy - 2012 - ChemBioChem - Wiley Online Library
Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription | eLife